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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3R3
All Species:
34.85
Human Site:
Y148
Identified Species:
95.83
UniProt:
Q92569
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92569
NP_001107644.1
461
54462
Y148
H
H
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Chimpanzee
Pan troglodytes
XP_517729
724
83607
Y416
R
N
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Rhesus Macaque
Macaca mulatta
XP_001107121
461
54420
Y148
H
H
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Dog
Lupus familis
XP_539629
461
54435
Y148
H
H
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64143
461
54456
Y148
H
H
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Rat
Rattus norvegicus
Q63789
461
54236
Y148
H
H
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426652
737
84066
Y423
R
N
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Frog
Xenopus laevis
Q8UUU2
722
83110
Y415
R
N
E
S
L
A
Q
Y
N
P
K
L
D
V
K
Zebra Danio
Brachydanio rerio
NP_957437
464
54712
Y150
R
H
E
S
L
A
Q
Y
N
T
K
L
D
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
99.5
98.9
N.A.
96
95
N.A.
N.A.
55.7
48.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.9
99.5
99.3
N.A.
98.4
97.6
N.A.
N.A.
60.6
56
93.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
56
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
100
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
0
0
0
0
100
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% Q
% Arg:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _